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In Silico Testing of Anthraquinone in Moringa Leaf (Moringa Oleifera) as a Natural Antidiabetic Compound

EasyChair Preprint 8891

7 pagesDate: October 2, 2022

Abstract

The purpose of this research is to ascertain the bioactivity of the anthraquinone compound found in Moringa (Moringa Oleifera) leaves as a naturally occurring antidiabetic substance.The literature was used to determine the anthraquinone compound's chemical structure, which is found in Moringa oleifera leaves. The control substance was metformin, and the target protein was p38 MAPK (Mitogen-Activated Protein Kinase). PyMol v2.5.2 Software was used to eliminate water molecules. Using PyRx-Python Prescription 0.8 Software, docking between the chemical and the target protein was performed. Compared to metformin, a control molecule, the findings indicated that the anthraquinone compound had a stronger potential as an antidiabetic. Anthraquinone has a relative p38 MAPK (Mitogen-Activated Protein Kinase) affinity of -7.3, whereas metformin has a relative p38 MAPK (Mitogen-Activated Protein Kinase) affinity of -5.5.

Keyphrases: Metformin, Moringa oleifera, anthraquinone, antidiabetic, p38 MAPK

BibTeX entry
BibTeX does not have the right entry for preprints. This is a hack for producing the correct reference:
@booklet{EasyChair:8891,
  author    = {Andi Ariyandy and Nindrahayu and Liong Boy Kurniawan and Andi Irwan Muluk and Aryadi Arsyad},
  title     = {In Silico Testing of Anthraquinone in Moringa Leaf (Moringa Oleifera) as a Natural Antidiabetic Compound},
  howpublished = {EasyChair Preprint 8891},
  year      = {EasyChair, 2022}}
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