Download PDFOpen PDF in browserDevelopment of Humanized Mouse and Rat Models with Full-Thickness Human Skin and Autologous Immune CellsEasyChair Preprint 122524 pages•Date: February 24, 2024AbstractThe development of humanized animal models has become increasingly crucial in biomedical research to bridge the gap between preclinical studies and human clinical trials. This research article focuses on the innovative approach of creating humanized mouse and rat models with full-thickness human skin and autologous immune cells. This methodology aims to enhance the translational relevance of preclinical studies by providing a more accurate representation of the human immune system and skin physiology. Keyphrases: Autologous Immune Cells, Humanized Mouse, Rat Models
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