Download PDFOpen PDF in browserChemical Biology of DiseaseEasyChair Preprint 1505916 pages•Date: September 25, 2024AbstractChemical biology is an interdisciplinary field that bridges chemistry and biology to understand disease mechanisms at the molecular level and develop innovative therapeutic strategies. It focuses on how small molecules interact with biological systems, altering pathways that lead to diseases like cancer, neurodegenerative disorders, and infectious diseases. Through chemical biology, scientists can manipulate cellular processes to identify drug targets, map signaling pathways, and discover biomarkers for early diagnosis. This abstract highlights the field's role in understanding disease etiology, its contribution to drug discovery, and the potential for precision medicine by tailoring treatments based on individual molecular profiles. Moreover, advances in chemical biology tools, such as high-throughput screening and chemical genetics, have accelerated the development of small-molecule modulators, offering novel solutions to traditionally intractable diseases. By integrating chemistry with the complexities of biology, chemical biology holds great promise in revolutionizing the approach to diagnosing, understanding, and treating human diseases. Keyphrases: BET, Bromodomain, Epigenetics, cancer, dual inhibitor, inhibitor, kinase
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