Synthesis, Characterization, and Activity of Phenothiazine Schiff Bases Containing Fluorine

EasyChair Preprint 6616

Abstract

This paper presents the synthesis of a series of Schiff bases derived from phenothiazine derivatives with fluorine benzaldehydes. The compounds were characterized physicochemically by NMR and IR spectroscopy, and their parameters were determined by appropriate methods. Their antimicrobial activity against various microorganisms were studied. One of the compounds showed weak activity against Bacillus subtilis and Salmonella abony. The rest were not active against the microorganisms used. The corrosion characteristics of the obtained compounds were studied using electrochemical techniques (cyclic voltammetry, polarization curves and impedance spectroscopy) in a three-electrode corrosion cell relative to (hydrogen reference electrode) RHE. The samples were applied to an experimental, ground graphite electrode using a spray technique with a thickness of about 50 µm. A detailed analysis of the internal resistance was carried out, including equivalent model schemes and experimental data.

Keyphrases: Antimicrobial activity, Corrosion, Schiff bases, phenothiazine, synthesis

@booklet{EasyChair:6616,
  author    = {Iliana Nikolova and Iliana Kostova and Temenuzhka Haralanova and Galin Borisov and Marin Marinov and Neyko Stoyanov},
  title     = {Synthesis, Characterization, and Activity of Phenothiazine Schiff Bases Containing Fluorine},
  howpublished = {EasyChair Preprint 6616},
  year      = {EasyChair, 2021}}